Manchester, New Hampshire was originally inhabited by the Amoskeag and Pennacook Indians. However, the arrival of European settlers caused the Indians to disperse throughout the country.

Manchester had three previous names, specifically Tyngstown, Harrytown and Derryfield. It was Thomas Stickney, John G. Moor and Most Weston who helped change Derryfield to Manchester. Other famous Manchester people include General John Stark, Samuel Blodget and Adam Sandler. Also associated with Manchester were William Gamble, Benjamin Hadlye, Nathaniel Martin and John Ridell.